e-Drug3D

2180

BAXDROSTAT

INN
BAXDROSTAT

cas 1428652-17-8

CLASS

CARDIOVASCULAR
ALDOSTERONE SYNTHASE INHIBITOR
TREATMENT OF HYPERTENSION

ROUTE (list)

ORAL

ATC code

C02KN02

PK parameters

F 98 PERCENT
Tmax 2.5 HOUR
VD 205 LITER
Cl 2.8 LITER / HOUR
PPB 74 PERCENT
t1/2 26 HOUR

Target

TARGET ALDOSTERONE SYNTHASE

Download SDF file

Propanamide, N-[(8R)-5,6,7,8-tetrahydro-4-(1,2,3,4-tetrahydro-1-methyl-2-oxo-6-quinolinyl)-8-isoquinolinyl]-

Formula:
C22H25N3O2

Calculated chemical properties:

MW 363.45
NB_atoms 27
XLogP 3.56
PSA 56.053
NB_HD 1
NB_HA 5
fsp3 0.41
Lipinski(0=no;1=yes) 1

FDA
NDA 219878 (label) INN (BAXDROSTAT) BAXFENDY (ASTRAZENECA AB) APPROVAL= AP YEAR= 2026 NEWMOLECULARENTITY