e-Drug3D

2171

PALTUSOTINE

INN
PALTUSOTINE

cas 2172870-89-0

CLASS

HORMONES
SOMATOSTATIN RECEPTOR AGONIST
TREATMENT OF ADULTS WITH ACROMEGALY

ROUTE (list)

ORAL

ATC code

H01CB06

PK parameters

Tmax 2.5 HOUR
VD 220 LITER
PPB 99 PERCENT
t1/2 28 HOUR

Target

TARGET SOMATOSTATIN RECEPTOR (SSTR2)

PDB
7YAC (PALTUSOTINE-BOUND SSTR2-GI COMPLEX)

Download experimental 3D coordinates of IUD with added hydrogens

Download SDF file

Benzonitrile, 3-[4-(4-amino-1-piperidinyl)-3-(3,5-difluorophenyl)-6-quinolinyl]-2-hydroxy-

Formula:
C27H22F2N4O

Calculated chemical properties:

MW 456.49
NB_atoms 34
XLogP 5.35
PSA 77.423
NB_HD 3
NB_HA 5
fsp3 0.19
Lipinski(0=no;1=yes) 0

FDA
NDA 219070 (label) INN (PALTUSOTINE HYDROCHLORIDE) PALSONIFY (CRINETICS) APPROVAL= AP YEAR= 2025 NEWMOLECULARENTITY