e-Drug3D

217

ETHOXZOLAMIDE

DISCONTINUED

INN
ETHOXZOLAMIDE

cas 452-35-7

CLASS

CARDIOVASCULAR
DIURETIC

ROUTE (list)

ORAL

ATC code

PK parameters

Target

TARGET CARBONIC ANHYDRASE

PDB
5TT3 (CRYSTAL STRUCTURE OF THE COMPLEX OF HELICOBACTER PYLORI ALPHA-CARBONIC ANHYDRASE WITH ETHOXZOLAMIDE)

Ligand code = EZL (link to the list of PDB complexes)

Download experimental 3D coordinates of EZL with added hydrogens

DrugCentral

Carbonic anhydrase 2 UNIPROT P00918 CA2

Carbonic anhydrase 1 UNIPROT P00915 CA1

Download SDF file

6-ethoxy-1,3-benzothiazole-2-sulfonamide

Formula:
C9H10N2O3S2

Calculated chemical properties:

MW 258.33
NB_atoms 16
XLogP 1.34
PSA 82.094
NB_HD 2
NB_HA 5
fsp3 0.22
Lipinski(0=no;1=yes) 1

FDA
NDA 011047 (pdf not found) INN (ETHOXZOLAMIDE) CARDRASE (PHARMACIA AND UPJOHN) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 016144 (pdf not found) INN (ETHOXZOLAMIDE) ETHAMIDE (ALLERGAN) APPROVAL= AP YEAR= 1966 DISCONTINUED