e-Drug3D

2166

ISLATRAVIR

INN
ISLATRAVIR

cas 865363-93-5

CLASS

ANTIINFECTIVES
A NUCLEOSIDE ANALOG REVERSE TRANSCRIPTASE INHIBITOR (NRTI)
TREATMENT OF HIV-1 INFECTION

ROUTE (list)

ORAL

ATC code

PK parameters

Tmax 1 HOUR
VD 264 LITER
Cl 27.7 LITER / HOUR
PPB 3 PERCENT
t1/2 21 HOUR

Solubility

VERY SLIGHTLY SOLUBLE IN WATER

Target

TARGET REVERSE TRANSCRIPTASE

Download SDF file

Adenosine, 2-deoxy-4-C-ethynyl-2-fluoro-

Formula:
C12H12FN5O3

Calculated chemical properties:

MW 293.27
NB_atoms 21
XLogP -0.81
PSA 111.089
NB_HD 4
NB_HA 8
fsp3 0.42
Lipinski(0=no;1=yes) 1

FDA
NDA 216964 (label) INN (DORAVIRINE ; ISLATRAVIR) IDVYNSO (MSD) APPROVAL= AP YEAR= 2026