e-Drug3D

2164

TEBIPENEM PIVOXIL

INN
TEBIPENEM PIVOXIL

(has an active metabolite)

cas 161715-24-8

CLASS

ANTIINFECTIVES
PENEM ANTIBACTERIAL PRODRUG FOR THE TREATMENT OF COMPLICATED URINARY TRACT INFECTIONS (CUTI)

ROUTE (list)

ORAL

ATC code

J01DH06

PK parameters

Solubility

SPARINGLY SOLUBLE IN WATER

Target

TARGET PENICILLIN-BINDING PROTEINS (PBPS)

DrugCentral

Unknown

Download SDF file

1-Azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 3-[[1-(4,5-dihydro-2-thiazolyl)-3-azetidinyl]thio]-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-, (2,2-dimethyl-1-oxopropoxy)methyl ester

Formula:
C22H31N3O6S2

Calculated chemical properties:

MW 497.64
NB_atoms 33
XLogP 1.67
PSA 108.361
NB_HD 1
NB_HA 9
fsp3 0.73
Lipinski(0=no;1=yes) 1

FDA
NDA 215960 (label) INN (TEBIPENEM PIVOXIL HYDROBROMIDE) UTEBZI (GLAXOSMITHKLINE) APPROVAL= AP YEAR= 2026 NEWMOLECULARENTITY