e-Drug3D

2139

SULOPENEM ETZADROXIL

INN
SULOPENEM ETZADROXIL

(has an active metabolite)

cas 1000296-70-7

CLASS

ANTIINFECTIVES
PENEM ANTIBACTERIAL
TREATMENT OF UNCOMPLICATED URINARY TRACT INFECTIONS (UUTI)

ROUTE (list)

ORAL

ATC code

PK parameters

Target

TARGET ESTERASE

DrugCentral

Download SDF file

4-Thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid, 6-[(1R)-1-hydroxyethyl]-7-oxo-3-[[(1R,3S)-tetrahydro-1-oxido-3-thienyl]thio]-, (2-ethyl-1-oxobutoxy)methyl ester, (5R,6S)- (ACI)

Formula:
C19H27NO7S3

Calculated chemical properties:

MW 477.63
NB_atoms 30
XLogP 1.80
PSA 108.255
NB_HD 1
NB_HA 8
fsp3 0.74
Lipinski(0=no;1=yes) 1

FDA
NDA 213972 (label) INN (PROBENECID ; SULOPENEM ETZADROXIL) ORLYNVAH (ITERUM THERAP) APPROVAL= AP YEAR= 2024