e-Drug3D

212

BUCLIZINE

DISCONTINUED

INN
BUCLIZINE

cas 82-95-1

CLASS

RESPIRATORY
ANTIEMETIC
ANTICHOLINERGIC AGENTS
ANTIHISTAMINES

ROUTE (list)

ORAL

PK parameters

Target

TARGET HISTAMINE H1 RECEPTOR

Histamine H1 receptor UNIPROT P35367 HRH1

Download SDF file

1-[(4-tert-butylphenyl)methyl]-4-[(4-chlorophenyl)-phenylmethyl]piperazine

Formula:
C28H33ClN2

Calculated chemical properties:

MW 433.01
NB_atoms 31
XLogP 6.54
PSA 9.424
NB_HD 0
NB_HA 2
fsp3 0.36
Lipinski(0=no;1=yes) 0

FDA
NDA 010911 (pdf not found) INN (BUCLIZINE HYDROCHLORIDE) BUCLADIN-S (STUART PHARMS) APPROVAL= AP YEAR= 1957 DISCONTINUED