e-Drug3D

2111

CEFTOBIPROLE MEDOCARIL

INN
CEFTOBIPROLE MEDOCARIL

cas 376653-43-9

CLASS

ANTIINFECTIVES
CEPHALOSPORIN ANTIBACTERIAL
TREATMENT OF STAPHYLOCOCCUS AUREUS BLOODSTREAM INFECTIONS
INHIBITION OF BACTERIAL CELL WALL SYNTHESIS
INHIBITION OF TRANSPEPTIDASE ACTIVITY

ROUTE (list)

INTRAVENOUS

ATC code

J01DI01

PK parameters

Target

TARGET PENICILLIN-BINDING PROTEINS (PBPS)

DrugCentral

MecA UNIPROT Q7DHH4 mecA

Download SDF file

5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-(hydroxyimino)acetyl]amino]-3-[(E)-[(3R)-1-[[(5-methyl-2-oxo-1,3-dioxol-4-yl)methoxy]carbonyl]-2-oxo[1,3-bipyrrolidin]-3-ylidene]methyl]-8-oxo-, (6R,7R)- (ACI)

Formula:
C26H26N8O11S2

Calculated chemical properties:

MW 689.68
NB_atoms 47
XLogP -1.87
PSA 238.987
NB_HD 4
NB_HA 19
fsp3 0.42
Lipinski(0=no;1=yes) 0

FDA
NDA 218275 (label) INN (CEFTOBIPROLE MEDOCARIL SODIUM) ZEVTERA (ISTX) APPROVAL= AP YEAR= 2024