e-Drug3D

2053

MARIBAVIR

INN
MARIBAVIR

cas 176161-24-3

CLASS

ANTIINFECTIVES
TREATMENT OF CYTOMEGALOVIRUS (CMV) PUL97 KINASE INHIBITOR

ROUTE (list)

ORAL

ATC code

J05AX10

PK parameters

Tmax 2 HOUR
VD 27.3 LITER
Cl 2.8 LITER / HOUR
PPB 98 PERCENT
t1/2 4.3 HOUR

Target

TARGET PUL97 KINASE

Serine threonine protein kinase UL97 UNIPROT P16788 UL97

Download SDF file

1H-Benzimidazol-2-amine, 5,6-dichloro-N-(1-methylethyl)-1-beta-L-ribofuranosyl- (9CI, ACI)

Formula:
C15H19Cl2N3O4

Calculated chemical properties:

MW 376.23
NB_atoms 24
XLogP 1.77
PSA 96.05
NB_HD 4
NB_HA 7
fsp3 0.53
Lipinski(0=no;1=yes) 1

FDA
NDA 215596 (label) INN (MARIBAVIR) LIVTENCITY (TAKEDA PHARMS USA) APPROVAL= AP YEAR= 2021