e-Drug3D

2047

M MOBOCERTINIB

INN
MOBOCERTINIB

(is an active metabolite)

cas 1847462-25-2

CLASS

ANTINEOPLASTIC
KINASE INHIBITOR
TREATMENT OF NSCLC WITH EGFR EXON 20 INSERTION MUTATIONS

ROUTE (list)

ATC code

L01EB10

PK parameters

Cl 149 LITER / HOUR
PPB 99.5 PERCENT
t1/2 24 HOUR

Target

TARGET EPIDERMAL GROWTH FACTOR RECEPTOR (EGFR) (MUTATED)

DrugCentral

Epidermal growth factor receptor UNIPROT P00533

Download SDF file

5-Pyrimidinecarboxylic acid, 2-[[2-methoxy-4-[methyl[2-(methylamino)ethyl]amino]-5-[(1-oxo-2-propen-1-yl)amino]phenyl]amino]-4-(1-methyl-1H-indol-3-yl)-, 1-methylethyl ester

Formula:
C31H37N7O4

Calculated chemical properties:

MW 571.68
NB_atoms 42
XLogP 4.73
PSA 112.798
NB_HD 3
NB_HA 11
fsp3 0.29
Lipinski(0=no;1=yes) 0

FDA
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