e-Drug3D
203
MECLIZINE
INN
MECLIZINE
cas 569-65-3
CLASS
RESPIRATORY SYSTEM
ANTI-ALLERGIC AGENTS
ANTIHISTAMINES
HISTAMINE H1 ANTAGONISTS
ROUTE (list)
ORAL
PK parameters
Tmax 3 HOUR
Cl 59 LITER / HOUR
t1/2 5.5 HOUR
TARGET HISTAMINE H1 RECEPTOR
Histamine H1 receptor UNIPROT P35367 HRH1
Formula:
C25H27ClN2
Calculated chemical properties:
MW 390.94
NB_atoms 28
XLogP 5.56
PSA 9.924
NB_HD 0
NB_HA 2
fsp3 0.28
Lipinski(0=no;1=yes) 0
NB_atoms 28
XLogP 5.56
PSA 9.924
NB_HD 0
NB_HA 2
fsp3 0.28
Lipinski(0=no;1=yes) 0
FDA
NDA 084382 (pdf not found) INN (MECLIZINE HYDROCHLORIDE) MECLIZINE HYDROCHLORIDE (BUNDY) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 085195 (pdf not found) INN (MECLIZINE HYDROCHLORIDE) MECLIZINE HYDROCHLORIDE (WATSON LABS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 088256 (pdf not found) INN (MECLIZINE HYDROCHLORIDE) MECLIZINE HYDROCHLORIDE (UDL) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 088257 (pdf not found) INN (MECLIZINE HYDROCHLORIDE) MECLIZINE HYDROCHLORIDE (UDL) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 089113 (pdf not found) INN (MECLIZINE HYDROCHLORIDE) MECLIZINE HYDROCHLORIDE (SUPERPHARM) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 010721 (label) INN (MECLIZINE HYDROCHLORIDE) ANTIVERT (CASPER PHARMA LLC) APPROVAL= AP YEAR= 1957
NDA 083784 (pdf not found) INN (MECLIZINE HYDROCHLORIDE) MECLIZINE HYDROCHLORIDE (IVAX SUB TEVA PHARMS) APPROVAL= AP YEAR= 1975 DISCONTINUED
NDA 084092 (pdf not found) INN (MECLIZINE HYDROCHLORIDE) MECLIZINE HYDROCHLORIDE (SCIEGEN PHARMS) APPROVAL= AP YEAR= 1975
NDA 084657 (pdf not found) INN (MECLIZINE HYDROCHLORIDE) MECLIZINE HYDROCHLORIDE (ANI PHARMS) APPROVAL= AP YEAR= 1975 DISCONTINUED
NDA 084843 (pdf not found) INN (MECLIZINE HYDROCHLORIDE) MECLIZINE HYDROCHLORIDE (SANDOZ) APPROVAL= AP YEAR= 1976
NDA 084975 (pdf not found) INN (MECLIZINE HYDROCHLORIDE) MECLIZINE HYDROCHLORIDE (ANI PHARMS INC) APPROVAL= AP YEAR= 1976 DISCONTINUED OBSOLETE
NDA 084976 (pdf not found) INN (MECLIZINE HYDROCHLORIDE) MECLIZINE HYDROCHLORIDE (IVAX SUB TEVA PHARMS) APPROVAL= AP YEAR= 1976 DISCONTINUED
NDA 085269 (pdf not found) INN (MECLIZINE HYDROCHLORIDE) MECLIZINE HYDROCHLORIDE (ANI PHARMS) APPROVAL= AP YEAR= 1976 DISCONTINUED
NDA 085252 (pdf not found) INN (MECLIZINE HYDROCHLORIDE) MECLIZINE HYDROCHLORIDE (ABC HOLDING) APPROVAL= AP YEAR= 1977 DISCONTINUED
NDA 085253 (pdf not found) INN (MECLIZINE HYDROCHLORIDE) MECLIZINE HYDROCHLORIDE (ABC HOLDING) APPROVAL= AP YEAR= 1977 DISCONTINUED
NDA 085523 (pdf not found) INN (MECLIZINE HYDROCHLORIDE) MECLIZINE HYDROCHLORIDE (KV PHARM) APPROVAL= AP YEAR= 1977 DISCONTINUED
NDA 085524 (pdf not found) INN (MECLIZINE HYDROCHLORIDE) MECLIZINE HYDROCHLORIDE (KV PHARM) APPROVAL= AP YEAR= 1977 DISCONTINUED
NDA 085740 (pdf not found) INN (MECLIZINE HYDROCHLORIDE) MECLIZINE HYDROCHLORIDE (ANI PHARMS) APPROVAL= AP YEAR= 1977 DISCONTINUED
NDA 084872 (pdf not found) INN (MECLIZINE HYDROCHLORIDE) MECLIZINE HYDROCHLORIDE (BUNDY) APPROVAL= AP YEAR= 1978 DISCONTINUED
NDA 085891 (pdf not found) INN (MECLIZINE HYDROCHLORIDE) MECLIZINE HYDROCHLORIDE (ANABOLIC) APPROVAL= AP YEAR= 1978 DISCONTINUED
NDA 086392 (pdf not found) INN (MECLIZINE HYDROCHLORIDE) MECLIZINE HYDROCHLORIDE (NEXGEN PHARMA INC) APPROVAL= AP YEAR= 1978 DISCONTINUED
NDA 087127 (pdf not found) INN (MECLIZINE HYDROCHLORIDE) MECLIZINE HYDROCHLORIDE (AUREX) APPROVAL= AP YEAR= 1981 OBSOLETE
NDA 087128 (pdf not found) INN (MECLIZINE HYDROCHLORIDE) MECLIZINE HYDROCHLORIDE (SENORES PHARMS) APPROVAL= AP YEAR= 1981
NDA 087620 (pdf not found) INN (MECLIZINE HYDROCHLORIDE) MECLIZINE HYDROCHLORIDE (VANGARD) APPROVAL= AP YEAR= 1982 DISCONTINUED
NDA 087877 (pdf not found) INN (MECLIZINE HYDROCHLORIDE) MECLIZINE HYDROCHLORIDE (VANGARD) APPROVAL= AP YEAR= 1982 DISCONTINUED
NDA 088732 (pdf not found) INN (MECLIZINE HYDROCHLORIDE) MECLIZINE HYDROCHLORIDE (ANI PHARMS) APPROVAL= AP YEAR= 1985 DISCONTINUED
NDA 088733 (pdf not found) INN (MECLIZINE HYDROCHLORIDE) MECLIZINE HYDROCHLORIDE (PLIVA) APPROVAL= AP YEAR= 1985 DISCONTINUED
NDA 088734 (pdf not found) INN (MECLIZINE HYDROCHLORIDE) MECLIZINE HYDROCHLORIDE (PLIVA) APPROVAL= AP YEAR= 1985 DISCONTINUED
NDA 089114 (pdf not found) INN (MECLIZINE HYDROCHLORIDE) MECLIZINE HYDROCHLORIDE (SUPERPHARM) APPROVAL= AP YEAR= 1985 DISCONTINUED
NDA 089674 (pdf not found) INN (MECLIZINE HYDROCHLORIDE) MECLIZINE HYDROCHLORIDE (STRIDES PHARMA INTL) APPROVAL= AP YEAR= 1988 DISCONTINUED
NDA 040179 (pdf not found) INN (MECLIZINE HYDROCHLORIDE) MECLIZINE HYDROCHLORIDE (RISING) APPROVAL= AP YEAR= 1997 DISCONTINUED
NDA 040659 (pdf not found) INN (MECLIZINE HYDROCHLORIDE) MECLIZINE HYDROCHLORIDE (JUBILANT CADISTA) APPROVAL= AP YEAR= 2010
NDA 201451 (pdf not found) INN (MECLIZINE HYDROCHLORIDE) MECLIZINE HYDROCHLORIDE (AMNEAL PHARMS) APPROVAL= AP YEAR= 2011
NDA 200294 (pdf not found) INN (MECLIZINE HYDROCHLORIDE) MECLIZINE HYDROCHLORIDE (EPIC PHARMA LLC) APPROVAL= AP YEAR= 2012
NDA 202640 (pdf not found) INN (MECLIZINE HYDROCHLORIDE) MECLIZINE HYDROCHLORIDE (AUROBINDO PHARMA USA) APPROVAL= AP YEAR= 2012
NDA 205136 (pdf not found) INN (MECLIZINE HYDROCHLORIDE) MECLIZINE HYDROCHLORIDE (HERITAGE) APPROVAL= AP YEAR= 2019
NDA 213957 (pdf not found) INN (MECLIZINE HYDROCHLORIDE) MECLIZINE HYDROCHLORIDE (ZYDUS LIFESCIENCES) APPROVAL= AP YEAR= 2020
NDA 200432 (pdf not found) INN (MECLIZINE HYDROCHLORIDE) MECLIZINE HYDROCHLORIDE (INVAGEN PHARMS) APPROVAL= AP YEAR= 2022 DISCONTINUED
NDA 200791 (pdf not found) INN (MECLIZINE HYDROCHLORIDE) MECLIZINE HYDROCHLORIDE (INVAGEN PHARMS) APPROVAL= AP YEAR= 2022 DISCONTINUED
NDA 203003 (pdf not found) INN (MECLIZINE HYDROCHLORIDE) MECLIZINE HYDROCHLORIDE (CHARTWELL RX) APPROVAL= AP YEAR= 2022
NDA 084382 (pdf not found) INN (MECLIZINE HYDROCHLORIDE) MECLIZINE HYDROCHLORIDE (BUNDY) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 085195 (pdf not found) INN (MECLIZINE HYDROCHLORIDE) MECLIZINE HYDROCHLORIDE (WATSON LABS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 088256 (pdf not found) INN (MECLIZINE HYDROCHLORIDE) MECLIZINE HYDROCHLORIDE (UDL) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 088257 (pdf not found) INN (MECLIZINE HYDROCHLORIDE) MECLIZINE HYDROCHLORIDE (UDL) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 089113 (pdf not found) INN (MECLIZINE HYDROCHLORIDE) MECLIZINE HYDROCHLORIDE (SUPERPHARM) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 010721 (label) INN (MECLIZINE HYDROCHLORIDE) ANTIVERT (CASPER PHARMA LLC) APPROVAL= AP YEAR= 1957
NDA 083784 (pdf not found) INN (MECLIZINE HYDROCHLORIDE) MECLIZINE HYDROCHLORIDE (IVAX SUB TEVA PHARMS) APPROVAL= AP YEAR= 1975 DISCONTINUED
NDA 084092 (pdf not found) INN (MECLIZINE HYDROCHLORIDE) MECLIZINE HYDROCHLORIDE (SCIEGEN PHARMS) APPROVAL= AP YEAR= 1975
NDA 084657 (pdf not found) INN (MECLIZINE HYDROCHLORIDE) MECLIZINE HYDROCHLORIDE (ANI PHARMS) APPROVAL= AP YEAR= 1975 DISCONTINUED
NDA 084843 (pdf not found) INN (MECLIZINE HYDROCHLORIDE) MECLIZINE HYDROCHLORIDE (SANDOZ) APPROVAL= AP YEAR= 1976
NDA 084975 (pdf not found) INN (MECLIZINE HYDROCHLORIDE) MECLIZINE HYDROCHLORIDE (ANI PHARMS INC) APPROVAL= AP YEAR= 1976 DISCONTINUED OBSOLETE
NDA 084976 (pdf not found) INN (MECLIZINE HYDROCHLORIDE) MECLIZINE HYDROCHLORIDE (IVAX SUB TEVA PHARMS) APPROVAL= AP YEAR= 1976 DISCONTINUED
NDA 085269 (pdf not found) INN (MECLIZINE HYDROCHLORIDE) MECLIZINE HYDROCHLORIDE (ANI PHARMS) APPROVAL= AP YEAR= 1976 DISCONTINUED
NDA 085252 (pdf not found) INN (MECLIZINE HYDROCHLORIDE) MECLIZINE HYDROCHLORIDE (ABC HOLDING) APPROVAL= AP YEAR= 1977 DISCONTINUED
NDA 085253 (pdf not found) INN (MECLIZINE HYDROCHLORIDE) MECLIZINE HYDROCHLORIDE (ABC HOLDING) APPROVAL= AP YEAR= 1977 DISCONTINUED
NDA 085523 (pdf not found) INN (MECLIZINE HYDROCHLORIDE) MECLIZINE HYDROCHLORIDE (KV PHARM) APPROVAL= AP YEAR= 1977 DISCONTINUED
NDA 085524 (pdf not found) INN (MECLIZINE HYDROCHLORIDE) MECLIZINE HYDROCHLORIDE (KV PHARM) APPROVAL= AP YEAR= 1977 DISCONTINUED
NDA 085740 (pdf not found) INN (MECLIZINE HYDROCHLORIDE) MECLIZINE HYDROCHLORIDE (ANI PHARMS) APPROVAL= AP YEAR= 1977 DISCONTINUED
NDA 084872 (pdf not found) INN (MECLIZINE HYDROCHLORIDE) MECLIZINE HYDROCHLORIDE (BUNDY) APPROVAL= AP YEAR= 1978 DISCONTINUED
NDA 085891 (pdf not found) INN (MECLIZINE HYDROCHLORIDE) MECLIZINE HYDROCHLORIDE (ANABOLIC) APPROVAL= AP YEAR= 1978 DISCONTINUED
NDA 086392 (pdf not found) INN (MECLIZINE HYDROCHLORIDE) MECLIZINE HYDROCHLORIDE (NEXGEN PHARMA INC) APPROVAL= AP YEAR= 1978 DISCONTINUED
NDA 087127 (pdf not found) INN (MECLIZINE HYDROCHLORIDE) MECLIZINE HYDROCHLORIDE (AUREX) APPROVAL= AP YEAR= 1981 OBSOLETE
NDA 087128 (pdf not found) INN (MECLIZINE HYDROCHLORIDE) MECLIZINE HYDROCHLORIDE (SENORES PHARMS) APPROVAL= AP YEAR= 1981
NDA 087620 (pdf not found) INN (MECLIZINE HYDROCHLORIDE) MECLIZINE HYDROCHLORIDE (VANGARD) APPROVAL= AP YEAR= 1982 DISCONTINUED
NDA 087877 (pdf not found) INN (MECLIZINE HYDROCHLORIDE) MECLIZINE HYDROCHLORIDE (VANGARD) APPROVAL= AP YEAR= 1982 DISCONTINUED
NDA 088732 (pdf not found) INN (MECLIZINE HYDROCHLORIDE) MECLIZINE HYDROCHLORIDE (ANI PHARMS) APPROVAL= AP YEAR= 1985 DISCONTINUED
NDA 088733 (pdf not found) INN (MECLIZINE HYDROCHLORIDE) MECLIZINE HYDROCHLORIDE (PLIVA) APPROVAL= AP YEAR= 1985 DISCONTINUED
NDA 088734 (pdf not found) INN (MECLIZINE HYDROCHLORIDE) MECLIZINE HYDROCHLORIDE (PLIVA) APPROVAL= AP YEAR= 1985 DISCONTINUED
NDA 089114 (pdf not found) INN (MECLIZINE HYDROCHLORIDE) MECLIZINE HYDROCHLORIDE (SUPERPHARM) APPROVAL= AP YEAR= 1985 DISCONTINUED
NDA 089674 (pdf not found) INN (MECLIZINE HYDROCHLORIDE) MECLIZINE HYDROCHLORIDE (STRIDES PHARMA INTL) APPROVAL= AP YEAR= 1988 DISCONTINUED
NDA 040179 (pdf not found) INN (MECLIZINE HYDROCHLORIDE) MECLIZINE HYDROCHLORIDE (RISING) APPROVAL= AP YEAR= 1997 DISCONTINUED
NDA 040659 (pdf not found) INN (MECLIZINE HYDROCHLORIDE) MECLIZINE HYDROCHLORIDE (JUBILANT CADISTA) APPROVAL= AP YEAR= 2010
NDA 201451 (pdf not found) INN (MECLIZINE HYDROCHLORIDE) MECLIZINE HYDROCHLORIDE (AMNEAL PHARMS) APPROVAL= AP YEAR= 2011
NDA 200294 (pdf not found) INN (MECLIZINE HYDROCHLORIDE) MECLIZINE HYDROCHLORIDE (EPIC PHARMA LLC) APPROVAL= AP YEAR= 2012
NDA 202640 (pdf not found) INN (MECLIZINE HYDROCHLORIDE) MECLIZINE HYDROCHLORIDE (AUROBINDO PHARMA USA) APPROVAL= AP YEAR= 2012
NDA 205136 (pdf not found) INN (MECLIZINE HYDROCHLORIDE) MECLIZINE HYDROCHLORIDE (HERITAGE) APPROVAL= AP YEAR= 2019
NDA 213957 (pdf not found) INN (MECLIZINE HYDROCHLORIDE) MECLIZINE HYDROCHLORIDE (ZYDUS LIFESCIENCES) APPROVAL= AP YEAR= 2020
NDA 200432 (pdf not found) INN (MECLIZINE HYDROCHLORIDE) MECLIZINE HYDROCHLORIDE (INVAGEN PHARMS) APPROVAL= AP YEAR= 2022 DISCONTINUED
NDA 200791 (pdf not found) INN (MECLIZINE HYDROCHLORIDE) MECLIZINE HYDROCHLORIDE (INVAGEN PHARMS) APPROVAL= AP YEAR= 2022 DISCONTINUED
NDA 203003 (pdf not found) INN (MECLIZINE HYDROCHLORIDE) MECLIZINE HYDROCHLORIDE (CHARTWELL RX) APPROVAL= AP YEAR= 2022