e-Drug3D

201

MEPENZOLATE

DISCONTINUED

INN
MEPENZOLATE

cas 25990-43-6

CLASS

METABOLISM
ANTICHOLINERGIC
PARASYMPATHOLYTICS
DIMINISHES GASTRIC ACID AND PEPSIN SECRETION
TREATMENT OF PEPTIC ULCER
MUSCARINIC RECEPTOR ANTAGONIST

ROUTE (list)

ORAL

ATC code

A03AB12

PK parameters

Solubility

SLIGHTLY SOLUBLE IN WATER

Target

TARGET MUSCARINIC RECEPTOR

Muscarinic acetylcholine receptor M1 UNIPROT P11229 CHRM1

Muscarinic acetylcholine receptor M3 UNIPROT P20309 CHRM3

Download SDF file

(1,1-dimethylpiperidin-1-ium-3-yl) 2-hydroxy-2,2-di(phenyl)acetate

Formula:
C21H26NO3

Calculated chemical properties:

MW 340.43
NB_atoms 25
XLogP 2.70
PSA 40.852
NB_HD 1
NB_HA 3
fsp3 0.38
Lipinski(0=no;1=yes) 1

FDA
NDA 010679 (label) INN (MEPENZOLATE BROMIDE) CANTIL (SANOFI AVENTIS US) APPROVAL= AP YEAR= 1956 NEWMOLECULARENTITY DISCONTINUED