e-Drug3D

2000

VIBEGRON

INN
VIBEGRON

cas 1190389-15-1

CLASS

MUSCULO-SKELETAL
TREATMENT OF OVERACTIVE BLADDER (OAB)
INCREASES BLADDER CAPACITY BY RELAXING THE DETRUSOR SMOOTH MUSCLE DURING BLADDER FILLING

ROUTE (list)

ORAL

ATC code

G04BD15

PK parameters

Tmax 2 HOUR
VD 6304 LITER
PPB 50 PERCENT
t1/2 30.8 HOUR

Target

TARGET BETA-3 ADRENERGIC RECEPTOR

Beta-3 adrenergic receptor UNIPROT P13945 ADRB3

Download SDF file

Pyrrolo[1,2-a]pyrimidine-6-carboxamide, 4,6,7,8-tetrahydro-N-[4-[[(2S,5R)-5-[(R)-hydroxyphenylmethyl]-2-pyrrolidinyl]methyl]phenyl]-4-oxo-, (6S)-

Formula:
C26H28N4O3

Calculated chemical properties:

MW 444.52
NB_atoms 33
XLogP 2.77
PSA 86.876
NB_HD 3
NB_HA 7
fsp3 0.35
Lipinski(0=no;1=yes) 1

FDA
NDA 213006 (label) INN (VIBEGRON) GEMTESA (SUMITOMO PHARMA AM) APPROVAL= AP YEAR= 2020 NEWMOLECULARENTITY