e-Drug3D

1796

M CARIPRAZINE

INN
CARIPRAZINE

cas 839712-25-3

CLASS

NERVOUS SYSTEM
ANTIPSYCHOTIC
TREATMENT OF SCHIZOPHRENIA
PARTIAL AGONIST DOPAMINE D2 RECEPTOR
PARTIAL AGONIST SEROTONIN 5-HT1A RECEPTOR
ANTAGONIST 5-HT2A RECEPTOR
HISTAMINE H1 RECEPTOR

ROUTE (list)

ATC code

N05AX15

PK parameters

Cmax 80 NANOMOLAR
PPB 94 PERCENT
t1/2 336 HOUR

Target

TARGET DOPAMINE D2 RECEPTOR
5-HT1A RECEPTOR

DrugCentral

D(2) dopamine receptor UNIPROT P14416 DRD2

5-hydroxytryptamine receptor 1A UNIPROT P08908 HTR1A

Download SDF file

Urea, N-[trans-4-[2-[4-(2,3-dichlorophenyl)-1-piperazinyl]ethyl]cyclohexyl]-

Formula:
C19H28Cl2N4O

Calculated chemical properties:

MW 399.35
NB_atoms 26
XLogP 3.73
PSA 64.062
NB_HD 3
NB_HA 5
fsp3 0.63
Lipinski(0=no;1=yes) 1

FDA
-