e-Drug3D

1795

M CARIPRAZINE

INN
CARIPRAZINE

cas 839712-15-1

CLASS

NERVOUS SYSTEM
ANTIPSYCHOTIC
TREATMENT OF SCHIZOPHRENIA
PARTIAL AGONIST DOPAMINE D2 RECEPTOR
PARTIAL AGONIST SEROTONIN 5-HT1A RECEPTOR
ANTAGONIST 5-HT2A RECEPTOR
HISTAMINE H1 RECEPTOR

ROUTE (list)

ATC code

N05AX15

PK parameters

Cmax 10 NANOMOLAR
PPB 94 PERCENT

Target

TARGET DOPAMINE D2 RECEPTOR
5-HT1A RECEPTOR

DrugCentral

D(2) dopamine receptor UNIPROT P14416 DRD2

5-hydroxytryptamine receptor 1A UNIPROT P08908 HTR1A

Download SDF file

Urea, N-[trans-4-[2-[4-(2,3-dichlorophenyl)-1-piperazinyl]ethyl]cyclohexyl]-N'-methyl-

Formula:
C20H30Cl2N4O

Calculated chemical properties:

MW 413.38
NB_atoms 27
XLogP 3.99
PSA 52.494
NB_HD 2
NB_HA 5
fsp3 0.65
Lipinski(0=no;1=yes) 1

FDA
-