e-Drug3D

1777

FLORBETABEN

INN
FLORBETABEN

cas 902143-01-5

CLASS

VARIOUS
DIAGNOSTIC
IMAGING AGENT
BINDS TO BETA-AMYLOID PLAQUES (KD = 16 NANOMOLAR)

ROUTE (list)

INTRAVENOUS

ATC code

PK parameters

PPB 98.5 PERCENT
t1/2 1.83 HOUR

Target

TARGET BETA-AMYLOID PLAQUE

Amyloid-beta precursor protein UNIPROT P05067 APP

Download SDF file

Benzenamine, 4-[(1E)-2-[4-[2-[2-[2-(fluoro-18F)ethoxy]ethoxy]ethoxy]phenyl]ethenyl]-N-methyl-

Formula:
C21H26FNO3

Calculated chemical properties:

MW 359.43
NB_atoms 26
XLogP 4.28
PSA 45.76
NB_HD 1
NB_HA 4
fsp3 0.33
Lipinski(0=no;1=yes) 1

FDA
NDA 204677 (label) INN (FLORBETABEN F-18) NEURACEQ (LANTHEUS) APPROVAL= AP YEAR= 2014