e-Drug3D

1775

FLORBETAPIR

INN
FLORBETAPIR

cas 956103-76-7

CLASS

VARIOUS
DIAGNOSTIC
IMAGING AGENT
BINDS TO BETA-AMYLOID PLAQUES (KD = 3.7 NANOMOLAR)

ROUTE (list)

INTRAVENOUS

ATC code

PK parameters

Target

TARGET BETA-AMYLOID PLAQUE

Amyloid-beta precursor protein UNIPROT P05067 APP

Download SDF file

Benzenamine, 4-[(1E)-2-[6-[2-[2-[2-(fluoro-18F)ethoxy]ethoxy]ethoxy]-3-pyridinyl]ethenyl]-N-methyl-

Formula:
C20H25FN2O3

Calculated chemical properties:

MW 360.42
NB_atoms 26
XLogP 3.68
PSA 53.76
NB_HD 1
NB_HA 5
fsp3 0.35
Lipinski(0=no;1=yes) 1

FDA
NDA 202008 (label) INN (FLORBETAPIR F-18) AMYVID (AVID RADIOPHARMS INC) APPROVAL= AP YEAR= 2012