e-Drug3D

1752

M CARBAMAZEPINE

INN
CARBAMAZEPINE

cas 36507-30-9

CLASS

NERVOUS SYSTEM
ANTICONVULSANT
ANALGESIC
ANTIMANIC AGENTS
SPECIFIC ANALGESIC FOR TRIGEMINAL NEURALGIA
CARBAMAZEPINE INDUCES ITS OWN METABOLISM
MECHANISM OF ACTION UNKNOWN (NUMEROUS PHARMACOLOGICAL EFFECTS HAVE BEEN DESCRIBED MODULATION OF ION CHANNELS (SODIUM AND CALCIUM), RECEPTOR-MEDIATED NEUROTRANSMISSION (GABAERGIC, GLUTAMATERGIC, AND MONOAMINERGIC), AND INTRACELLULAR SIGNALING PATHWAYS)

ROUTE (list)

ATC code

N03AF01

PK parameters

Tmax 14 HOUR
PPB 50 PERCENT
t1/2 34 HOUR

Target

TARGET VOLTAGE-GATED SODIUM CHANNELS

DrugCentral

Sodium channel protein type 5 subunit alpha UNIPROT Q14524 SCN5A

Sodium channel protein type 4 subunit alpha UNIPROT P35499 SCN4A

Download SDF file

6H-Dibenz[b,f]oxireno[d]azepine-6-carboxamide, 1a,10b-dihydro-

Formula:
C15H12N2O2

Calculated chemical properties:

MW 252.27
NB_atoms 19
XLogP 3.03
PSA 50.678
NB_HD 2
NB_HA 4
fsp3 0.13
Lipinski(0=no;1=yes) 1

FDA
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