e-Drug3D

1732

MILTEFOSINE

INN
MILTEFOSINE

cas 58066-85-6

CLASS

ANTIPARASITIC
TREATMENT OF LEISHMANIASIS
INTERACTION WITH LIPIDS (PHOSPHOLIPIDS AND STEROLS)
INHIBITION OF CYTOCHROME C OXIDASE
APOPTOSIS-LIKE CELL DEATH

ROUTE (list)

ORAL

ATC code

P01CX04

PK parameters

Tmax 7 HOUR
PPB 98 PERCENT
t1/2 153.6 HOUR

Solubility

FREELY SOLUBLE IN WATER

Target

TARGET MEMBRANE

DrugCentral

Unknown

Download SDF file

Ethanaminium, 2-[[(hexadecyloxy)hydroxyphosphinyl]oxy]-N,N,N-trimethyl-

Formula:
C21H47NO4P

Calculated chemical properties:

MW 407.56
NB_atoms 27
XLogP 5.68
PSA 54.137
NB_HD 0
NB_HA 4
fsp3 1.00
Lipinski(0=no;1=yes) 0

FDA
NDA 204684 (label) INN (MILTEFOSINE) IMPAVIDO (KNIGHT THERAPS) APPROVAL= AP YEAR= 2014 NEWMOLECULARENTITY