e-Drug3D

1652

M RIFAPENTINE

INN
RIFAPENTINE

cas 79039-56-8

CLASS

ANTIINFECTIVES
TUBERCULOSTATIC
ANTIBIOTIC
RIFAMYCIN ANTIMYCOBACTERIALS
INHIBITS DNA-DEPENDENT RNA POLYMERASE

ROUTE (list)

ATC code

J04AB05

PK parameters

Tmax 11.2 HOUR
Cmax 7.5 MICROMOLAR
PPB 93.2 PERCENT
t1/2 13 HOUR

Target

TARGET DNA-DIRECTED RNA POLYMERASE

Bacterial DNA-directed RNA polymerase UNIPROT P0A7Z4 rpoA

Download SDF file

Rifamycin, 3-[[(4-cyclopentyl-1-piperazinyl)imino]methyl]-25-O-deacetyl-

Formula:
C45H62N4O11

Calculated chemical properties:

MW 834.99
NB_atoms 60
XLogP 5.08
PSA 192.136
NB_HD 7
NB_HA 15
fsp3 0.58
Lipinski(0=no;1=yes) 0

FDA
-