e-Drug3D

1636

DAUNORUBICINOL

INN
DAUNORUBICINOL

cas 28008-55-1

CLASS

ANTINEOPLASTIC
ANTIBIOTICS
CYTOTOXIC
ANTIMITOTIC
ANTHRACYCLINES
INDICATED FOR REMISSION INDUCTION IN ACUTE NONLYMPHOCYTIC LEUKEMIA
INTERCALANT

ROUTE (list)

ATC code

L01XY01
L01DB02

PK parameters

t1/2 26.7 HOUR

Target

TARGET TOPOISOMERASE II
DNA
MULTIDRUG RESISTANCE PROTEIN 1
POLYMERASE

DrugCentral

DNA topoisomerase 2-alpha UNIPROT P11388 TOP2A

Download SDF file

5,12-Naphthacenedione, 10-[(3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-[(1S)-1-hydroxyethyl]-1-methoxy-, (8S,10S)-

Formula:
C27H31NO10

Calculated chemical properties:

MW 529.53
NB_atoms 38
XLogP 0.82
PSA 171.807
NB_HD 7
NB_HA 11
fsp3 0.48
Lipinski(0=no;1=yes) 0

FDA
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