e-Drug3D

1632

POLIDOCANOL

INN
POLIDOCANOL

cas 9002-92-0

CLASS

CARDIOVASCULAR
SCLEROSING AGENTS FOR LOCAL INJECTION
ANTIVARICOSE THERAPY
DAMAGING EFFECT ON THE ENDOTHELIUM OF BLOOD VESSELS
ATTACHES TO THE LIPID CELL MEMBRANE OF THE VENOUS ENDOTHELIUM, RESULTING IN DISRUPTION OF THE OSMOTIC BARRIER, DESTRUCTION OF THE VENOUS ENDOTHELIUM, AND VASOSPASM

ROUTE (list)

INTRAVENOUS

ATC code

C05BB02

PK parameters

VD 58.5 LITER
Cl 18 LITER / HOUR
t1/2 2.1 HOUR

Solubility

SOLUBLE IN WATER

Target

TARGET MEMBRANE

DrugCentral

Unknown

Download SDF file

Poly(oxy-1,2-ethanediyl), alpha-dodecyl-omega-hydroxy-

Formula:
C30H62O10

Calculated chemical properties:

MW 582.80
NB_atoms 40
XLogP 4.05
PSA 117.6
NB_HD 1
NB_HA 10
fsp3 1.00
Lipinski(0=no;1=yes) 0

FDA
NDA 021201 (label) INN (POLIDOCANOL) ASCLERA (CHEMISCH FBRK KRSSLR) APPROVAL= AP YEAR= 2010 NEWMOLECULARENTITY
NDA 205098 (label) INN (POLIDOCANOL) VARITHENA (BOSTON SCITFC) APPROVAL= AP YEAR= 2013