e-Drug3D
1497
DIENOGEST
INN
DIENOGEST
cas 65928-58-7
CLASS
GENITO
CONTRACEPTIVE
ROUTE (list)
ORAL
ATC code
G03FA15
PK parameters
F 91 PERCENT
VD 46 LITER (85 MICROGRAM IV)
Cl 2.9 LITER / HOUR (EQN)
PPB 90 PERCENT
t1/2 11 HOUR
TARGET PROGESTERONE RECEPTOR
Progesterone receptor UNIPROT P06401 PGR
Formula:
C20H25NO2
Calculated chemical properties:
MW 311.41
NB_atoms 23
XLogP 3.84
PSA 55.236
NB_HD 1
NB_HA 3
fsp3 0.70
Lipinski(0=no;1=yes) 1
NB_atoms 23
XLogP 3.84
PSA 55.236
NB_HD 1
NB_HA 3
fsp3 0.70
Lipinski(0=no;1=yes) 1
FDA
NDA 022252 (label) INN (DIENOGEST ; ESTRADIOL VALERATE) NATAZIA (BAYER HLTHCARE) APPROVAL= AP YEAR= 2010
NDA 202999 (pdf not found) INN (ESTRADIOL VALERATE ; ESTRADIOL VALERATE ; DIENOGEST) ESTRADIOL VALERATE; ESTRADIOL VALERATE; DIENOGEST (DR REDDYS LABS SA) APPROVAL= TA YEAR= 2016
NDA 202349 (pdf not found) INN (DIENOGEST ; ESTRADIOL VALERATE) ESTRADIOL VALERATE AND DIENOGEST (WATSON LABS INC) APPROVAL= TA YEAR= 2017
NDA 022252 (label) INN (DIENOGEST ; ESTRADIOL VALERATE) NATAZIA (BAYER HLTHCARE) APPROVAL= AP YEAR= 2010
NDA 202999 (pdf not found) INN (ESTRADIOL VALERATE ; ESTRADIOL VALERATE ; DIENOGEST) ESTRADIOL VALERATE; ESTRADIOL VALERATE; DIENOGEST (DR REDDYS LABS SA) APPROVAL= TA YEAR= 2016
NDA 202349 (pdf not found) INN (DIENOGEST ; ESTRADIOL VALERATE) ESTRADIOL VALERATE AND DIENOGEST (WATSON LABS INC) APPROVAL= TA YEAR= 2017