e-Drug3D
14
MEPERIDINE
INN
MEPERIDINE
cas 57-42-1
CLASS
NERVOUS SYSTEM
ADJUVANTS IN ANESTHESIA
ANALGESICS
OPIOID
NARCOTICS
OPIATE AGONISTS
ANTICHOLINERGIC
ROUTE (list)
ORAL INJECTION
ATC code
N02AB02
PK parameters
Cmax 1.38 MICROMOLAR (PMID2729638)
VD 149.5 LITER (65 KILOGRAM)
Cl 19.1 LITER / HOUR (65 KILOGRAM)
PPB 58 PERCENT
t1/2 7.9 HOUR
Solubility
READILY SOLUBLE IN WATER
TARGET MU-TYPE OPIOID RECEPTOR
Mu-type opioid receptor UNIPROT P35372 OPRM1
Formula:
C15H21NO2
Calculated chemical properties:
MW 247.33
NB_atoms 18
XLogP 2.21
PSA 27.726
NB_HD 0
NB_HA 3
fsp3 0.53
Lipinski(0=no;1=yes) 1
NB_atoms 18
XLogP 2.21
PSA 27.726
NB_HD 0
NB_HA 3
fsp3 0.53
Lipinski(0=no;1=yes) 1
FDA
NDA 080385 (pdf not found) INN (MEPERIDINE HYDROCHLORIDE) MEPERIDINE HYDROCHLORIDE (ABBOTT) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 080386 (pdf not found) INN (MEPERIDINE HYDROCHLORIDE) MEPERIDINE HYDROCHLORIDE (ABBOTT) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 080387 (pdf not found) INN (MEPERIDINE HYDROCHLORIDE) MEPERIDINE HYDROCHLORIDE (ABBOTT) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 080388 (pdf not found) INN (MEPERIDINE HYDROCHLORIDE) MEPERIDINE HYDROCHLORIDE (ABBOTT) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 080389 (pdf not found) INN (MEPERIDINE HYDROCHLORIDE) MEPERIDINE HYDROCHLORIDE (ABBOTT) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 085121 (pdf not found) INN (ATROPINE SULFATE ; MEPERIDINE HYDROCHLORIDE) MEPERIDINE AND ATROPINE SULFATE (WYETH AYERST) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 086332 (pdf not found) INN (MEPERIDINE HYDROCHLORIDE) MEPERIDINE HYDROCHLORIDE (INTL MEDICATION) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 087847 (pdf not found) INN (ATROPINE SULFATE ; MEPERIDINE HYDROCHLORIDE) ATROPINE AND DEMEROL (ABBVIE) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 087848 (pdf not found) INN (ATROPINE SULFATE ; MEPERIDINE HYDROCHLORIDE) ATROPINE AND DEMEROL (ABBVIE) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 087853 (pdf not found) INN (ATROPINE SULFATE ; MEPERIDINE HYDROCHLORIDE) ATROPINE AND DEMEROL (ABBVIE) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 089781 (pdf not found) INN (MEPERIDINE HYDROCHLORIDE) MEPERIDINE HYDROCHLORIDE (IGI LABS INC) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 089782 (pdf not found) INN (MEPERIDINE HYDROCHLORIDE) MEPERIDINE HYDROCHLORIDE (IGI LABS INC) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 089783 (pdf not found) INN (MEPERIDINE HYDROCHLORIDE) MEPERIDINE HYDROCHLORIDE (IGI LABS INC) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 089784 (pdf not found) INN (MEPERIDINE HYDROCHLORIDE) MEPERIDINE HYDROCHLORIDE (IGI LABS INC) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 089785 (pdf not found) INN (MEPERIDINE HYDROCHLORIDE) MEPERIDINE HYDROCHLORIDE (IGI LABS INC) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 089786 (pdf not found) INN (MEPERIDINE HYDROCHLORIDE) MEPERIDINE HYDROCHLORIDE (IGI LABS INC) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 089787 (pdf not found) INN (MEPERIDINE HYDROCHLORIDE) MEPERIDINE HYDROCHLORIDE (IGI LABS INC) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 089788 (pdf not found) INN (MEPERIDINE HYDROCHLORIDE) MEPERIDINE HYDROCHLORIDE (IGI LABS INC) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 005010 (label) INN (MEPERIDINE HYDROCHLORIDE) DEMEROL (QUAGEN) APPROVAL= AP YEAR= 1942 DISCONTINUED
NDA 021171 (label) INN (MEPERIDINE HYDROCHLORIDE) DEMEROL (HOSPIRA) APPROVAL= AP YEAR= 1942
NDA 011730 (label) INN (MEPERIDINE HYDROCHLORIDE ; PROMETHAZINE HYDROCHLORIDE) MEPERGAN (HIKMA) APPROVAL= AP YEAR= 1961 DISCONTINUED
NDA 080455 (pdf not found) INN (MEPERIDINE HYDROCHLORIDE) MEPERIDINE HYDROCHLORIDE (WEST-WARD PHARMS INT) APPROVAL= AP YEAR= 1972
NDA 080454 (pdf not found) INN (MEPERIDINE HYDROCHLORIDE) MEPERIDINE HYDROCHLORIDE (WYETH AYERST) APPROVAL= AP YEAR= 1973 DISCONTINUED
NDA 080445 (pdf not found) INN (MEPERIDINE HYDROCHLORIDE) MEPERIDINE HYDROCHLORIDE (WEST-WARD PHARMS INT) APPROVAL= AP YEAR= 1975
NDA 080364 (pdf not found) INN (MEPERIDINE HYDROCHLORIDE) MEPERIDINE HYDROCHLORIDE (PARKE DAVIS) APPROVAL= AP YEAR= 1976 DISCONTINUED
NDA 080448 (pdf not found) INN (MEPERIDINE HYDROCHLORIDE) MEPERIDINE HYDROCHLORIDE (SUN PHARM INDUSTRIES) APPROVAL= AP YEAR= 1976 DISCONTINUED
NDA 088279 (pdf not found) INN (MEPERIDINE HYDROCHLORIDE) MEPERIDINE HYDROCHLORIDE (BAXTER HLTHCARE) APPROVAL= AP YEAR= 1984 DISCONTINUED
NDA 088280 (pdf not found) INN (MEPERIDINE HYDROCHLORIDE) MEPERIDINE HYDROCHLORIDE (BAXTER HLTHCARE) APPROVAL= AP YEAR= 1984 DISCONTINUED
NDA 088281 (pdf not found) INN (MEPERIDINE HYDROCHLORIDE) MEPERIDINE HYDROCHLORIDE (BAXTER HLTHCARE) APPROVAL= AP YEAR= 1984 DISCONTINUED
NDA 088282 (pdf not found) INN (MEPERIDINE HYDROCHLORIDE) MEPERIDINE HYDROCHLORIDE (BAXTER HLTHCARE) APPROVAL= AP YEAR= 1984 DISCONTINUED
NDA 088432 (pdf not found) INN (MEPERIDINE HYDROCHLORIDE) MEPERIDINE HYDROCHLORIDE PRESERVATIVE FREE (ICU MEDICAL INC) APPROVAL= AP YEAR= 1984 DISCONTINUED
NDA 088639 (pdf not found) INN (MEPERIDINE HYDROCHLORIDE) MEPERIDINE HYDROCHLORIDE (BARR) APPROVAL= AP YEAR= 1984 DISCONTINUED
NDA 088640 (pdf not found) INN (MEPERIDINE HYDROCHLORIDE) MEPERIDINE HYDROCHLORIDE (BARR) APPROVAL= AP YEAR= 1984 DISCONTINUED
NDA 088744 (pdf not found) INN (MEPERIDINE HYDROCHLORIDE) MEPERIDINE HYDROCHLORIDE (HIKMA) APPROVAL= AP YEAR= 1985
NDA 073443 (pdf not found) INN (MEPERIDINE HYDROCHLORIDE) MEPERIDINE HYDROCHLORIDE PRESERVATIVE FREE (WATSON LABS) APPROVAL= AP YEAR= 1992 DISCONTINUED
NDA 073444 (pdf not found) INN (MEPERIDINE HYDROCHLORIDE) MEPERIDINE HYDROCHLORIDE (WATSON LABS) APPROVAL= AP YEAR= 1992 DISCONTINUED
NDA 073445 (pdf not found) INN (MEPERIDINE HYDROCHLORIDE) MEPERIDINE HYDROCHLORIDE (WATSON LABS) APPROVAL= AP YEAR= 1992 DISCONTINUED
NDA 081002 (pdf not found) INN (MEPERIDINE HYDROCHLORIDE) MEPERIDINE HYDROCHLORIDE PRESERVATIVE FREE (WEST-WARD PHARMS INT) APPROVAL= AP YEAR= 1993
NDA 081309 (pdf not found) INN (MEPERIDINE HYDROCHLORIDE) MEPERIDINE HYDROCHLORIDE PRESERVATIVE FREE (INTL MEDICATION) APPROVAL= AP YEAR= 1993 DISCONTINUED
NDA 040110 (pdf not found) INN (MEPERIDINE HYDROCHLORIDE) MEPERIDINE HYDROCHLORIDE (HIKMA) APPROVAL= AP YEAR= 1997 DISCONTINUED
NDA 040163 (pdf not found) INN (MEPERIDINE HYDROCHLORIDE) MEPERIDINE HYDROCHLORIDE PRESERVATIVE FREE (SPECGX LLC) APPROVAL= AP YEAR= 1997 DISCONTINUED
NDA 040186 (pdf not found) INN (MEPERIDINE HYDROCHLORIDE) MEPERIDINE HYDROCHLORIDE (WATSON LABS) APPROVAL= AP YEAR= 1997 DISCONTINUED
NDA 040191 (label) INN (MEPERIDINE HYDROCHLORIDE) MEPERIDINE HYDROCHLORIDE (STRIDES PHARMA INTL) APPROVAL= AP YEAR= 1998 DISCONTINUED
NDA 040305 (pdf not found) INN (MEPERIDINE HYDROCHLORIDE) MEPERIDINE HYDROCHLORIDE PRESERVATIVE FREE (HOSPIRA) APPROVAL= AP YEAR= 1999 DISCONTINUED
NDA 040318 (pdf not found) INN (MEPERIDINE HYDROCHLORIDE) MEPERIDINE HYDROCHLORIDE (DURAMED PHARMS BARR) APPROVAL= AP YEAR= 1999 DISCONTINUED
NDA 040331 (pdf not found) INN (MEPERIDINE HYDROCHLORIDE) MEPERIDINE HYDROCHLORIDE (EPIC PHARMA LLC) APPROVAL= AP YEAR= 1999
NDA 040352 (label) INN (MEPERIDINE HYDROCHLORIDE) MEPERIDINE HYDROCHLORIDE (SPECGX LLC) APPROVAL= AP YEAR= 2000 DISCONTINUED
NDA 040446 (pdf not found) INN (MEPERIDINE HYDROCHLORIDE) MEPERIDINE HYDROCHLORIDE (SUN PHARM INDS INC) APPROVAL= AP YEAR= 2002 DISCONTINUED
NDA 040893 (pdf not found) INN (MEPERIDINE HYDROCHLORIDE) MEPERIDINE HYDROCHLORIDE (GENUS) APPROVAL= AP YEAR= 2009
NDA 080385 (pdf not found) INN (MEPERIDINE HYDROCHLORIDE) MEPERIDINE HYDROCHLORIDE (ABBOTT) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 080386 (pdf not found) INN (MEPERIDINE HYDROCHLORIDE) MEPERIDINE HYDROCHLORIDE (ABBOTT) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 080387 (pdf not found) INN (MEPERIDINE HYDROCHLORIDE) MEPERIDINE HYDROCHLORIDE (ABBOTT) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 080388 (pdf not found) INN (MEPERIDINE HYDROCHLORIDE) MEPERIDINE HYDROCHLORIDE (ABBOTT) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 080389 (pdf not found) INN (MEPERIDINE HYDROCHLORIDE) MEPERIDINE HYDROCHLORIDE (ABBOTT) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 085121 (pdf not found) INN (ATROPINE SULFATE ; MEPERIDINE HYDROCHLORIDE) MEPERIDINE AND ATROPINE SULFATE (WYETH AYERST) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 086332 (pdf not found) INN (MEPERIDINE HYDROCHLORIDE) MEPERIDINE HYDROCHLORIDE (INTL MEDICATION) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 087847 (pdf not found) INN (ATROPINE SULFATE ; MEPERIDINE HYDROCHLORIDE) ATROPINE AND DEMEROL (ABBVIE) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 087848 (pdf not found) INN (ATROPINE SULFATE ; MEPERIDINE HYDROCHLORIDE) ATROPINE AND DEMEROL (ABBVIE) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 087853 (pdf not found) INN (ATROPINE SULFATE ; MEPERIDINE HYDROCHLORIDE) ATROPINE AND DEMEROL (ABBVIE) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 089781 (pdf not found) INN (MEPERIDINE HYDROCHLORIDE) MEPERIDINE HYDROCHLORIDE (IGI LABS INC) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 089782 (pdf not found) INN (MEPERIDINE HYDROCHLORIDE) MEPERIDINE HYDROCHLORIDE (IGI LABS INC) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 089783 (pdf not found) INN (MEPERIDINE HYDROCHLORIDE) MEPERIDINE HYDROCHLORIDE (IGI LABS INC) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 089784 (pdf not found) INN (MEPERIDINE HYDROCHLORIDE) MEPERIDINE HYDROCHLORIDE (IGI LABS INC) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 089785 (pdf not found) INN (MEPERIDINE HYDROCHLORIDE) MEPERIDINE HYDROCHLORIDE (IGI LABS INC) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 089786 (pdf not found) INN (MEPERIDINE HYDROCHLORIDE) MEPERIDINE HYDROCHLORIDE (IGI LABS INC) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 089787 (pdf not found) INN (MEPERIDINE HYDROCHLORIDE) MEPERIDINE HYDROCHLORIDE (IGI LABS INC) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 089788 (pdf not found) INN (MEPERIDINE HYDROCHLORIDE) MEPERIDINE HYDROCHLORIDE (IGI LABS INC) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 005010 (label) INN (MEPERIDINE HYDROCHLORIDE) DEMEROL (QUAGEN) APPROVAL= AP YEAR= 1942 DISCONTINUED
NDA 021171 (label) INN (MEPERIDINE HYDROCHLORIDE) DEMEROL (HOSPIRA) APPROVAL= AP YEAR= 1942
NDA 011730 (label) INN (MEPERIDINE HYDROCHLORIDE ; PROMETHAZINE HYDROCHLORIDE) MEPERGAN (HIKMA) APPROVAL= AP YEAR= 1961 DISCONTINUED
NDA 080455 (pdf not found) INN (MEPERIDINE HYDROCHLORIDE) MEPERIDINE HYDROCHLORIDE (WEST-WARD PHARMS INT) APPROVAL= AP YEAR= 1972
NDA 080454 (pdf not found) INN (MEPERIDINE HYDROCHLORIDE) MEPERIDINE HYDROCHLORIDE (WYETH AYERST) APPROVAL= AP YEAR= 1973 DISCONTINUED
NDA 080445 (pdf not found) INN (MEPERIDINE HYDROCHLORIDE) MEPERIDINE HYDROCHLORIDE (WEST-WARD PHARMS INT) APPROVAL= AP YEAR= 1975
NDA 080364 (pdf not found) INN (MEPERIDINE HYDROCHLORIDE) MEPERIDINE HYDROCHLORIDE (PARKE DAVIS) APPROVAL= AP YEAR= 1976 DISCONTINUED
NDA 080448 (pdf not found) INN (MEPERIDINE HYDROCHLORIDE) MEPERIDINE HYDROCHLORIDE (SUN PHARM INDUSTRIES) APPROVAL= AP YEAR= 1976 DISCONTINUED
NDA 088279 (pdf not found) INN (MEPERIDINE HYDROCHLORIDE) MEPERIDINE HYDROCHLORIDE (BAXTER HLTHCARE) APPROVAL= AP YEAR= 1984 DISCONTINUED
NDA 088280 (pdf not found) INN (MEPERIDINE HYDROCHLORIDE) MEPERIDINE HYDROCHLORIDE (BAXTER HLTHCARE) APPROVAL= AP YEAR= 1984 DISCONTINUED
NDA 088281 (pdf not found) INN (MEPERIDINE HYDROCHLORIDE) MEPERIDINE HYDROCHLORIDE (BAXTER HLTHCARE) APPROVAL= AP YEAR= 1984 DISCONTINUED
NDA 088282 (pdf not found) INN (MEPERIDINE HYDROCHLORIDE) MEPERIDINE HYDROCHLORIDE (BAXTER HLTHCARE) APPROVAL= AP YEAR= 1984 DISCONTINUED
NDA 088432 (pdf not found) INN (MEPERIDINE HYDROCHLORIDE) MEPERIDINE HYDROCHLORIDE PRESERVATIVE FREE (ICU MEDICAL INC) APPROVAL= AP YEAR= 1984 DISCONTINUED
NDA 088639 (pdf not found) INN (MEPERIDINE HYDROCHLORIDE) MEPERIDINE HYDROCHLORIDE (BARR) APPROVAL= AP YEAR= 1984 DISCONTINUED
NDA 088640 (pdf not found) INN (MEPERIDINE HYDROCHLORIDE) MEPERIDINE HYDROCHLORIDE (BARR) APPROVAL= AP YEAR= 1984 DISCONTINUED
NDA 088744 (pdf not found) INN (MEPERIDINE HYDROCHLORIDE) MEPERIDINE HYDROCHLORIDE (HIKMA) APPROVAL= AP YEAR= 1985
NDA 073443 (pdf not found) INN (MEPERIDINE HYDROCHLORIDE) MEPERIDINE HYDROCHLORIDE PRESERVATIVE FREE (WATSON LABS) APPROVAL= AP YEAR= 1992 DISCONTINUED
NDA 073444 (pdf not found) INN (MEPERIDINE HYDROCHLORIDE) MEPERIDINE HYDROCHLORIDE (WATSON LABS) APPROVAL= AP YEAR= 1992 DISCONTINUED
NDA 073445 (pdf not found) INN (MEPERIDINE HYDROCHLORIDE) MEPERIDINE HYDROCHLORIDE (WATSON LABS) APPROVAL= AP YEAR= 1992 DISCONTINUED
NDA 081002 (pdf not found) INN (MEPERIDINE HYDROCHLORIDE) MEPERIDINE HYDROCHLORIDE PRESERVATIVE FREE (WEST-WARD PHARMS INT) APPROVAL= AP YEAR= 1993
NDA 081309 (pdf not found) INN (MEPERIDINE HYDROCHLORIDE) MEPERIDINE HYDROCHLORIDE PRESERVATIVE FREE (INTL MEDICATION) APPROVAL= AP YEAR= 1993 DISCONTINUED
NDA 040110 (pdf not found) INN (MEPERIDINE HYDROCHLORIDE) MEPERIDINE HYDROCHLORIDE (HIKMA) APPROVAL= AP YEAR= 1997 DISCONTINUED
NDA 040163 (pdf not found) INN (MEPERIDINE HYDROCHLORIDE) MEPERIDINE HYDROCHLORIDE PRESERVATIVE FREE (SPECGX LLC) APPROVAL= AP YEAR= 1997 DISCONTINUED
NDA 040186 (pdf not found) INN (MEPERIDINE HYDROCHLORIDE) MEPERIDINE HYDROCHLORIDE (WATSON LABS) APPROVAL= AP YEAR= 1997 DISCONTINUED
NDA 040191 (label) INN (MEPERIDINE HYDROCHLORIDE) MEPERIDINE HYDROCHLORIDE (STRIDES PHARMA INTL) APPROVAL= AP YEAR= 1998 DISCONTINUED
NDA 040305 (pdf not found) INN (MEPERIDINE HYDROCHLORIDE) MEPERIDINE HYDROCHLORIDE PRESERVATIVE FREE (HOSPIRA) APPROVAL= AP YEAR= 1999 DISCONTINUED
NDA 040318 (pdf not found) INN (MEPERIDINE HYDROCHLORIDE) MEPERIDINE HYDROCHLORIDE (DURAMED PHARMS BARR) APPROVAL= AP YEAR= 1999 DISCONTINUED
NDA 040331 (pdf not found) INN (MEPERIDINE HYDROCHLORIDE) MEPERIDINE HYDROCHLORIDE (EPIC PHARMA LLC) APPROVAL= AP YEAR= 1999
NDA 040352 (label) INN (MEPERIDINE HYDROCHLORIDE) MEPERIDINE HYDROCHLORIDE (SPECGX LLC) APPROVAL= AP YEAR= 2000 DISCONTINUED
NDA 040446 (pdf not found) INN (MEPERIDINE HYDROCHLORIDE) MEPERIDINE HYDROCHLORIDE (SUN PHARM INDS INC) APPROVAL= AP YEAR= 2002 DISCONTINUED
NDA 040893 (pdf not found) INN (MEPERIDINE HYDROCHLORIDE) MEPERIDINE HYDROCHLORIDE (GENUS) APPROVAL= AP YEAR= 2009