e-Drug3D

1364

cas 6463-21-4

CLASS

CARDIOVASCULAR
DIURETIC
KETONE DERIVATIVE OF AN ARYLOXYACETIC ACID
TREATMENT OF EDEMA

ROUTE (list)

INJECTION ORAL

PK parameters

-

PDB
11GS (GLUTATHIONE S-TRANSFERASE COMPLEXED WITH ETHACRYNIC ACID-GLUTATHIONE CONJUGATE (FORM II))

Ligand code = EAA (link to the list of PDB complexes)

Download experimental 3D coordinates of EAA with added hydrogens

MW 302.12
NB_atoms 19
XLogP 2.27
PSA 63.28
NB_HD 0
NB_HA 4
fsp3 0.23
Lipinski(0=no;1=yes) 1

FDA
NDA 016093 (label) INN (ETHACRYNATE SODIUM) EDECRIN (BAUSCH) APPROVAL= AP YEAR= 1967
NDA 016092 (label) INN (ETHACRYNIC ACID) EDECRIN (BAUSCH) APPROVAL= AP YEAR= 1967
NDA 205473 (pdf not found) INN (ETHACRYNATE SODIUM) ETHACRYNATE SODIUM (PH HEALTH) APPROVAL= AP YEAR= 2015
NDA 205609 (label) INN (ETHACRYNIC ACID) ETHACRYNIC ACID (ADAPTIS) APPROVAL= AP YEAR= 2016
NDA 204634 (pdf not found) INN (ETHACRYNATE SODIUM) ETHACRYNATE SODIUM (MYLAN INSTITUTIONAL) APPROVAL= AP YEAR= 2016 DISCONTINUED
NDA 207262 (pdf not found) INN (ETHACRYNIC ACID) ETHACRYNIC ACID (HIKMA) APPROVAL= AP YEAR= 2017 DISCONTINUED
NDA 208501 (pdf not found) INN (ETHACRYNIC ACID) ETHACRYNIC ACID (PH HEALTH) APPROVAL= AP YEAR= 2017 DISCONTINUED
NDA 207758 (pdf not found) INN (ETHACRYNATE SODIUM) ETHACRYNATE SODIUM (ZYDUS PHARMS) APPROVAL= AP YEAR= 2017
NDA 208805 (pdf not found) INN (ETHACRYNIC ACID) ETHACRYNIC ACID (AMNEAL PHARMS CO) APPROVAL= AP YEAR= 2018
NDA 205709 (pdf not found) INN (ETHACRYNIC ACID) ETHACRYNIC ACID (ALVOGEN) APPROVAL= AP YEAR= 2018 DISCONTINUED
NDA 211232 (pdf not found) INN (ETHACRYNIC ACID) ETHACRYNIC ACID (SCIEGEN PHARMS) APPROVAL= AP YEAR= 2019
NDA 211719 (pdf not found) INN (ETHACRYNIC ACID) ETHACRYNIC ACID (LUPIN) APPROVAL= AP YEAR= 2019
NDA 211809 (pdf not found) INN (ETHACRYNIC ACID) ETHACRYNIC ACID (AGNITIO) APPROVAL= AP YEAR= 2019
NDA 212417 (pdf not found) INN (ETHACRYNIC ACID) ETHACRYNIC ACID (UPSHER SMITH LABS) APPROVAL= AP YEAR= 2020
NDA 208663 (pdf not found) INN (ETHACRYNATE SODIUM) ETHACRYNATE SODIUM (STERIMAX) APPROVAL= AP YEAR= 2020
NDA 213240 (pdf not found) INN (ETHACRYNIC ACID) ETHACRYNIC ACID (CHARTWELL RX) APPROVAL= AP YEAR= 2020