e-Drug3D

1352

LEVOPROPOXYPHENE

DISCONTINUED

INN
LEVOPROPOXYPHENE

cas 2338-37-6

CLASS

NERVOUS SYSTEM
ANTITUSSIVE
OPIOID AGONIST
ANALGESIC

ROUTE (list)

ORAL

ATC code

N02AC04
N02AC54
N02AC74

PK parameters

Tmax 2.25 HOUR
Cmax 0.21 MICROMOLAR (65 MILLIGRAM)
VD 780 LITER (65 KILOGRAM)
Cl 58.5 LITER / HOUR (65 KILOGRAM)
PPB 80 PERCENT
t1/2 9 HOUR

Solubility

FREELY SOLUBLE IN WATER

Target

TARGET SODIUM CHANNEL
HERG
OPIOID RECEPTOR

DrugCentral

Mu-type opioid receptor UNIPROT P35372 OPRM1

Download SDF file

Benzeneethanol, .alpha.-[(1S)-2-(dimethylamino)-1-methylethyl]-.alpha.-phenyl-, 1-propanoate, (.alpha.R)-

Formula:
C22H29NO2

Calculated chemical properties:

MW 339.46
NB_atoms 25
XLogP 4.28
PSA 22.915
NB_HD 0
NB_HA 3
fsp3 0.41
Lipinski(0=no;1=yes) 1

FDA
NDA 012928 (pdf not found) INN (LEVOPROPOXYPHENE NAPSYLATE ANHYDROUS) NOVRAD (LILLY) APPROVAL= AP YEAR= 1962 DISCONTINUED