e-Drug3D

1341

TRIAMCINOLONE HEXACETONIDE

DISCONTINUED

INN
TRIAMCINOLONE HEXACETONIDE

cas 5611-51-8

CLASS

GLUCOCORTICOID
AGONIST
ANTI-INFLAMMATORY AGENTS
ALOPECIA AREATA
CYSTIC TUMORS OF AN APONEUROSIS OR TENDON (GANGLIA)
ECZEMA
PSORIASIS
ARTHRITIS
ALLERGIES
ULCERATIVE COLITIS
LUPUS
SYMPATHETIC OPHTHALMIA
TEMPORAL ARTERITIS
UVEITIS
OCULAR INFLAMMATION

ROUTE (list)

INJECTION

ATC code

A01AC01
C05AA12
D07AB09
D07XB02
H02AB08
R01AD11
R03BA06
S01BA05
D07CB01
S02CA04
D07BB03

PK parameters

Solubility

RELATIVELY INSOLUBLE 0.0002 PERCENT AT 25 DEGRE CELSIUS IN WATER

Target

TARGET GLUCOCORTICOID RECEPTOR

DrugCentral

Glucocorticoid receptor UNIPROT P04150 NR3C1

Download SDF file

Pregna-1,4-diene-3,20-dione, 21-(3,3-dimethyl-1-oxobutoxy)-9-fluoro-11-hydroxy-16,17-[(1-methylethylidene)bis(oxy)]-, (11.beta.,16.alpha.)-

Formula:
C30H41FO7

Calculated chemical properties:

MW 532.63
NB_atoms 38
XLogP 4.41
PSA 86.447
NB_HD 1
NB_HA 7
fsp3 0.77
Lipinski(0=no;1=yes) 0

FDA
NDA 016466 (label) INN (TRIAMCINOLONE HEXACETONIDE) ARISTOSPAN (ETHYPHARM) APPROVAL= AP YEAR= 1969 DISCONTINUED