e-Drug3D

1298

cas 133099-04-4

CLASS

GENITO
ANTIINFLAMMATORY
MUSCARINIC ANTAGONISTS
URINARY ANTISPASMODICS

ROUTE (list)

ORAL

PK parameters

F 19 PERCENT
Cmax 23.4 NANOMOLAR (15 MILLIGRAM)
VD 163 LITER
Cl 40 LITER / HOUR
PPB 98 PERCENT
t1/2 16 HOUR

MW 426.54
NB_atoms 32
XLogP 3.96
PSA 54.302
NB_HD 2
NB_HA 4
fsp3 0.32
Lipinski(0=no;1=yes) 1

FDA
NDA 021513 (label) INN (DARIFENACIN HYDROBROMIDE) ENABLEX (ABBVIE) APPROVAL= AP YEAR= 2004 NEWMOLECULARENTITY DISCONTINUED
NDA 091190 (pdf not found) INN (DARIFENACIN HYDROBROMIDE) DARIFENACIN HYDROBROMIDE (PH HEALTH) APPROVAL= AP YEAR= 2015 DISCONTINUED
NDA 205209 (pdf not found) INN (DARIFENACIN HYDROBROMIDE) DARIFENACIN HYDROBROMIDE (TORRENT) APPROVAL= AP YEAR= 2016
NDA 205550 (pdf not found) INN (DARIFENACIN HYDROBROMIDE) DARIFENACIN HYDROBROMIDE (JUBILANT GENERICS) APPROVAL= AP YEAR= 2016 DISCONTINUED
NDA 206743 (pdf not found) INN (DARIFENACIN HYDROBROMIDE) DARIFENACIN HYDROBROMIDE (AUROBINDO PHARMA) APPROVAL= AP YEAR= 2016
NDA 207664 (pdf not found) INN (DARIFENACIN HYDROBROMIDE) DARIFENACIN HYDROBROMIDE (CIPLA) APPROVAL= AP YEAR= 2016
NDA 207302 (pdf not found) INN (DARIFENACIN HYDROBROMIDE) DARIFENACIN (MACLEODS PHARMS LTD) APPROVAL= AP YEAR= 2017
NDA 207681 (pdf not found) INN (DARIFENACIN HYDROBROMIDE) DARIFENACIN HYDROBROMIDE (ALEMBIC) APPROVAL= AP YEAR= 2017
NDA 209571 (pdf not found) INN (DARIFENACIN HYDROBROMIDE) DARIFENACIN HYDROBROMIDE (XIROMED) APPROVAL= AP YEAR= 2019 DISCONTINUED
NDA 211045 (pdf not found) INN (DARIFENACIN HYDROBROMIDE) DARIFENACIN HYDROBROMIDE (PURACAP LABS BLU) APPROVAL= AP YEAR= 2020