e-Drug3D

1250

cas 74191-85-8

CLASS

CARDIOVASCULAR
ADRENOCEPTOR (ALPHA1) ANTAGONIST
ANTIHYPERTENSIVE
VASODILATOR AGENTS
TREATMENT OF PROSTATIC HYPERPLASIA (BPH)

ROUTE (list)

ORAL

PK parameters

F 59 PERCENT
Cmax 57 NANOMOLAR (8 MILLIGRAM)
VD 84.5 LITER (65 KILOGRAM)
Cl 6.24 LITER / HOUR (65 KILOGRAM)
PPB 98 PERCENT
t1/2 17 HOUR

MW 451.48
NB_atoms 33
XLogP 1.72
PSA 107.234
NB_HD 2
NB_HA 10
fsp3 0.35
Lipinski(0=no;1=yes) 1

FDA
NDA 019668 (label) INN (DOXAZOSIN MESYLATE) CARDURA (VIATRIS) APPROVAL= AP YEAR= 1990
NDA 075426 (pdf not found) INN (DOXAZOSIN MESYLATE) DOXAZOSIN MESYLATE (WATSON LABS INC) APPROVAL= AP YEAR= 2000 DISCONTINUED
NDA 075432 (pdf not found) INN (DOXAZOSIN MESYLATE) DOXAZOSIN MESYLATE (ANI PHARMS) APPROVAL= AP YEAR= 2000 DISCONTINUED
NDA 075453 (pdf not found) INN (DOXAZOSIN MESYLATE) DOXAZOSIN MESYLATE (IVAX SUB TEVA PHARMS) APPROVAL= AP YEAR= 2000 DISCONTINUED
NDA 075466 (pdf not found) INN (DOXAZOSIN MESYLATE) DOXAZOSIN MESYLATE (GENPHARM) APPROVAL= AP YEAR= 2000 DISCONTINUED
NDA 075509 (pdf not found) INN (DOXAZOSIN MESYLATE) DOXAZOSIN MESYLATE (AUROBINDO PHARMA USA) APPROVAL= AP YEAR= 2000
NDA 075536 (pdf not found) INN (DOXAZOSIN MESYLATE) DOXAZOSIN MESYLATE (TEVA) APPROVAL= AP YEAR= 2000
NDA 075574 (pdf not found) INN (DOXAZOSIN MESYLATE) DOXAZOSIN MESYLATE (ACTAVIS ELIZABETH) APPROVAL= AP YEAR= 2000 DISCONTINUED
NDA 075580 (pdf not found) INN (DOXAZOSIN MESYLATE) DOXAZOSIN MESYLATE (APOTEX) APPROVAL= AP YEAR= 2000
NDA 075609 (label) INN (DOXAZOSIN MESYLATE) DOXAZOSIN MESYLATE (NESHER PHARMS) APPROVAL= AP YEAR= 2000 DISCONTINUED
NDA 075646 (pdf not found) INN (DOXAZOSIN MESYLATE) DOXAZOSIN MESYLATE (CHARTWELL RX) APPROVAL= AP YEAR= 2000 DISCONTINUED
NDA 075353 (pdf not found) INN (DOXAZOSIN MESYLATE) DOXAZOSIN MESYLATE (TEVA) APPROVAL= AP YEAR= 2001 DISCONTINUED
NDA 075750 (pdf not found) INN (DOXAZOSIN MESYLATE) DOXAZOSIN MESYLATE (PLIVA) APPROVAL= AP YEAR= 2001 DISCONTINUED
NDA 076161 (pdf not found) INN (DOXAZOSIN MESYLATE) DOXAZOSIN MESYLATE (STRIDES PHARMA INTL) APPROVAL= AP YEAR= 2004 DISCONTINUED
NDA 021269 (label) INN (DOXAZOSIN MESYLATE) CARDURA XL (VIATRIS) APPROVAL= AP YEAR= 2005
NDA 202824 (pdf not found) INN (DOXAZOSIN MESYLATE) DOXAZOSIN MESYLATE (ACCORD HLTHCARE) APPROVAL= AP YEAR= 2014
NDA 208719 (pdf not found) INN (DOXAZOSIN MESYLATE) DOXAZOSIN MESYLATE (ZYDUS PHARMS) APPROVAL= AP YEAR= 2017
NDA 205210 (pdf not found) INN (DOXAZOSIN MESYLATE) DOXAZOSIN MESYLATE (HERITAGE PHARMA) APPROVAL= AP YEAR= 2018
NDA 209013 (pdf not found) INN (DOXAZOSIN MESYLATE) DOXAZOSIN MESYLATE (SOMERSET THERAPS LLC) APPROVAL= AP YEAR= 2018
NDA 212727 (pdf not found) INN (DOXAZOSIN MESYLATE) DOXAZOSIN MESYLATE (RISING) APPROVAL= AP YEAR= 2022
NDA 212329 (pdf not found) INN (DOXAZOSIN MESYLATE) DOXAZOSIN MESYLATE (UNICHEM) APPROVAL= AP YEAR= 2024