e-Drug3D

1249

cas 83150-76-9

CLASS

HORMONES
HORMONE REPLACEMENT AGENTS
SOMATOSTATIN MIMICK
REDUCE BLOOD LEVELS OF GROWTH HORMONE AND IGF-I (SOMATOMEDIN C) IN ACROMEGALY PATIENTS
SYMPTOMATIC TREATMENT

ROUTE (list)

INJECTION ORAL SUBCUTANEOUS

PK parameters

Cmax 5.1 NANOMOLAR (100 MICROGRAM)
VD 13.6 LITER
Cl 8.5 LITER / HOUR
PPB 65 PERCENT
t1/2 1.8 HOUR

MW 1019.26
NB_atoms 71
XLogP -0.81
PSA 279.232
NB_HD 15
NB_HA 20
fsp3 0.45
Lipinski(0=no;1=yes) 0

FDA
NDA 019667 (label) INN (OCTREOTIDE ACETATE) SANDOSTATIN (NOVARTIS) APPROVAL= AP YEAR= 1988
NDA 021008 (label) INN (OCTREOTIDE ACETATE) SANDOSTATIN LAR (NOVARTIS) APPROVAL= AP YEAR= 1998
NDA 075957 (pdf not found) INN (OCTREOTIDE ACETATE) OCTREOTIDE ACETATE (MEITHEAL) APPROVAL= AP YEAR= 2005
NDA 075959 (pdf not found) INN (OCTREOTIDE ACETATE) OCTREOTIDE ACETATE (MEITHEAL) APPROVAL= AP YEAR= 2005
NDA 076313 (pdf not found) INN (OCTREOTIDE ACETATE) OCTREOTIDE ACETATE PRESERVATIVE FREE (WEST-WARD PHARMS INT) APPROVAL= AP YEAR= 2005
NDA 076330 (pdf not found) INN (OCTREOTIDE ACETATE) OCTREOTIDE ACETATE (WEST-WARD PHARMS INT) APPROVAL= AP YEAR= 2005
NDA 077450 (pdf not found) INN (OCTREOTIDE ACETATE) OCTREOTIDE ACETATE (FRESENIUS KABI USA) APPROVAL= AP YEAR= 2006
NDA 077457 (pdf not found) INN (OCTREOTIDE ACETATE) OCTREOTIDE ACETATE PRESERVATIVE FREE (FRESENIUS KABI USA) APPROVAL= AP YEAR= 2006
NDA 077372 (pdf not found) INN (OCTREOTIDE ACETATE) OCTREOTIDE ACETATE (SUN PHARM INDS) APPROVAL= AP YEAR= 2007 DISCONTINUED
NDA 077373 (pdf not found) INN (OCTREOTIDE ACETATE) OCTREOTIDE ACETATE (SUN PHARM INDS) APPROVAL= AP YEAR= 2007 DISCONTINUED
NDA 077329 (pdf not found) INN (OCTREOTIDE ACETATE) OCTREOTIDE ACETATE (SUN PHARM INDS) APPROVAL= AP YEAR= 2008 DISCONTINUED
NDA 077330 (pdf not found) INN (OCTREOTIDE ACETATE) OCTREOTIDE ACETATE (SUN PHARM INDS) APPROVAL= AP YEAR= 2008 DISCONTINUED
NDA 077331 (pdf not found) INN (OCTREOTIDE ACETATE) OCTREOTIDE ACETATE (SUN PHARM INDS) APPROVAL= AP YEAR= 2008 DISCONTINUED
NDA 079198 (pdf not found) INN (OCTREOTIDE ACETATE) OCTREOTIDE ACETATE PRESERVATIVE FREE (MYLAN INSTITUTIONAL) APPROVAL= AP YEAR= 2011
NDA 090985 (pdf not found) INN (OCTREOTIDE ACETATE) OCTREOTIDE ACETATE PRESERVATIVE FREE (WOCKHARDT USA) APPROVAL= AP YEAR= 2011 DISCONTINUED
NDA 090986 (pdf not found) INN (OCTREOTIDE ACETATE) OCTREOTIDE ACETATE (WOCKHARDT USA) APPROVAL= AP YEAR= 2011 DISCONTINUED
NDA 090834 (pdf not found) INN (OCTREOTIDE ACETATE) OCTREOTIDE ACETATE PRESERVATIVE FREE (SAGENT PHARMS INC) APPROVAL= AP YEAR= 2013
NDA 091041 (pdf not found) INN (OCTREOTIDE ACETATE) OCTREOTIDE ACETATE (SAGENT PHARMS INC) APPROVAL= AP YEAR= 2013
NDA 203765 (pdf not found) INN (OCTREOTIDE ACETATE) OCTREOTIDE ACETATE (HERITAGE) APPROVAL= AP YEAR= 2018
NDA 204669 (pdf not found) INN (OCTREOTIDE ACETATE) OCTREOTIDE ACETATE (HERITAGE) APPROVAL= AP YEAR= 2018
NDA 208232 (label) INN (OCTREOTIDE ACETATE) MYCAPSSA (CHIESI) APPROVAL= AP YEAR= 2020
NDA 216807 (pdf not found) INN (OCTREOTIDE ACETATE) OCTREOTIDE ACETATE (GLAND) APPROVAL= AP YEAR= 2023
NDA 216839 (pdf not found) INN (OCTREOTIDE ACETATE) OCTREOTIDE ACETATE (GLAND) APPROVAL= AP YEAR= 2023
NDA 210317 (pdf not found) INN (OCTREOTIDE ACETATE) OCTREOTIDE ACETATE (TEVA PHARMS USA INC) APPROVAL= AP YEAR= 2023
NDA 213224 (label) INN (OCTREOTIDE ACETATE) BYNFEZIA PEN (SUN PHARM) APPROVAL= AP YEAR= 2024
NDA 217860 (pdf not found) INN (OCTREOTIDE ACETATE) OCTREOTIDE ACETATE (SHUANGCHENG) APPROVAL= AP YEAR= 2024 DISCONTINUED
NDA 216589 (pdf not found) INN (OCTREOTIDE ACETATE) OCTREOTIDE ACETATE (MYLAN LABS LTD) APPROVAL= AP YEAR= 2025