e-Drug3D

1248

PIPECURONIUM

DISCONTINUED

INN
PIPECURONIUM

cas 68399-58-6

CLASS

MUSCULO-SKELETAL SYSTEM
MUSCLE RELAXANT
NEUROMUSCULAR NONDEPOLARIZING AGENTS
CHOLINERGIC RECEPTOR
NICOTINIC RECEPTOR ANTAGONISTS
CURARIFORM FAMILY
ANESTHESIA

ROUTE (list)

INJECTION

ATC code

M03AC06

PK parameters

VD 16.2 LITER (65 KILOGRAM)
Cl 7.8 LITER / HOUR (65 KILOGRAM)
PPB 2 PERCENT
t1/2 1.7 HOUR

Target

TARGET NEURONAL ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA-2

DrugCentral

Acetylcholine receptor UNIPROT P02708 CHRNA1

Download SDF file

[(2S,3S,5S,8R,9S,10S,13S,14S,16S,17R)-3-acetyloxy-2,16-bis(4,4-dimethylpiperazin-4-ium-1-yl)-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl] acetate

Formula:
C35H62N4O4

Calculated chemical properties:

MW 602.89
NB_atoms 43
XLogP 3.63
PSA 53.394
NB_HD 0
NB_HA 6
fsp3 0.94
Lipinski(0=no;1=yes) 0

FDA
NDA 019638 (pdf not found) INN (PIPECURONIUM BROMIDE) ARDUAN (ORGANON USA INC) APPROVAL= AP YEAR= 1990 DISCONTINUED