e-Drug3D

1037

STREPTOZOCIN

DISCONTINUED

INN
STREPTOZOCIN

cas 18883-66-4

CLASS

ANTINEOPLASTIC
ALKYLATING AGENTS
NITROSOUREAS

ROUTE (list)

INJECTION

ATC code

L01AD04

PK parameters

t1/2 0.58 HOUR

Target

TARGET DNA

PDB
2W4X (BTGH84 IN COMPLEX WITH STZ)

Download experimental 3D coordinates of STZ with added hydrogens

Unknown

Download SDF file

1-methyl-1-nitroso-3-[(2S,3R,4R,5S,6R)-2,4,5-trihydroxy-6-(hydroxymethyl)oxan-3-yl]urea

Formula:
C8H15N3O7

Calculated chemical properties:

MW 265.23
NB_atoms 18
XLogP -2.89
PSA 152.461
NB_HD 5
NB_HA 10
fsp3 0.88
Lipinski(0=no;1=yes) 0

FDA
NDA 050577 (pdf not found) INN (STREPTOZOCIN) ZANOSAR (TEVA PHARMS USA) APPROVAL= AP YEAR= 1982 DISCONTINUED