e-Drug3D

1008

cas 25953-19-9

CLASS

ANTIINFECTIVES
ANTIBACTERIAL
ANTIBIOTIC
CEPHALOSPORINS

ROUTE (list)

INJECTION INTRAVENOUS

PK parameters

Tmax 0.25 HOUR (2 GRAM)
Cmax 407 MICROMOLAR (1 GRAM)
VD 7.8 LITER (65 KILOGRAM)
Cl 3.4 LITER / HOUR
PPB 82 PERCENT
t1/2 1.8 HOUR

TARGET PENICILLIN-BINDING PROTEINS 1A/1B

PDB
8YXA (CRYSTAL STRUCTURE OF THE HSA COMPLEX WITH CEFAZOLIN AND MYRISTATE)

Ligand code = X56 (link to the list of PDB complexes)

Download experimental 3D coordinates of X56 with added hydrogens

MW 453.53
NB_atoms 29
XLogP -1.97
PSA 148.352
NB_HD 1
NB_HA 12
fsp3 0.43
Lipinski(0=no;1=yes) 0

FDA
NDA 050566 (pdf not found) INN (CEFAZOLIN SODIUM) ANCEF IN SODIUM CHLORIDE 0.9% IN PLASTIC CONTAINER (BAXTER HLTHCARE) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 062688 (pdf not found) INN (CEFAZOLIN SODIUM) CEFAZOLIN SODIUM (ABRAXIS PHARM) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 062894 (pdf not found) INN (CEFAZOLIN SODIUM) CEFAZOLIN SODIUM (BEDFORD) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 063018 (pdf not found) INN (CEFAZOLIN SODIUM) CEFAZOLIN SODIUM (TEVA PHARMS) APPROVAL= - YEAR= 0 DISCONTINUED
NDA 050461 (label) INN (CEFAZOLIN SODIUM) ANCEF (GLAXOSMITHKLINE) APPROVAL= AP YEAR= 1973 DISCONTINUED
NDA 061773 (pdf not found) INN (CEFAZOLIN SODIUM) KEFZOL (ACS DOBFAR) APPROVAL= AP YEAR= 1973 DISCONTINUED
NDA 062557 (pdf not found) INN (CEFAZOLIN SODIUM) KEFZOL (LILLY) APPROVAL= AP YEAR= 1985 DISCONTINUED
NDA 062807 (pdf not found) INN (CEFAZOLIN SODIUM) CEFAZOLIN SODIUM (HIKMA) APPROVAL= AP YEAR= 1988 DISCONTINUED
NDA 062831 (pdf not found) INN (CEFAZOLIN SODIUM) CEFAZOLIN SODIUM (SANDOZ) APPROVAL= AP YEAR= 1988
NDA 062988 (pdf not found) INN (CEFAZOLIN SODIUM) CEFAZOLIN SODIUM (DR REDDYS) APPROVAL= AP YEAR= 1989 DISCONTINUED
NDA 062989 (pdf not found) INN (CEFAZOLIN SODIUM) CEFAZOLIN SODIUM (DR REDDYS) APPROVAL= AP YEAR= 1989 DISCONTINUED
NDA 063016 (pdf not found) INN (CEFAZOLIN SODIUM) CEFAZOLIN SODIUM (TEVA PHARMS) APPROVAL= AP YEAR= 1989 DISCONTINUED
NDA 063002 (pdf not found) INN (CEFAZOLIN SODIUM) ANCEF IN PLASTIC CONTAINER (BAXTER HLTHCARE) APPROVAL= AP YEAR= 1991 DISCONTINUED
NDA 063207 (pdf not found) INN (CEFAZOLIN SODIUM) CEFAZOLIN SODIUM (FACTA FARMA) APPROVAL= AP YEAR= 1991 DISCONTINUED
NDA 063208 (pdf not found) INN (CEFAZOLIN SODIUM) CEFAZOLIN SODIUM (STERI PHARMA) APPROVAL= AP YEAR= 1991 DISCONTINUED
NDA 063209 (pdf not found) INN (CEFAZOLIN SODIUM) CEFAZOLIN SODIUM (FACTA FARMA) APPROVAL= AP YEAR= 1991 DISCONTINUED
NDA 063214 (pdf not found) INN (CEFAZOLIN SODIUM) CEFAZOLIN SODIUM (FACTA FARMA) APPROVAL= AP YEAR= 1991 DISCONTINUED
NDA 063216 (pdf not found) INN (CEFAZOLIN SODIUM) CEFAZOLIN SODIUM (STERI PHARMA) APPROVAL= AP YEAR= 1991 DISCONTINUED
NDA 064033 (pdf not found) INN (CEFAZOLIN SODIUM) CEFAZOLIN SODIUM (GLAXOSMITHKLINE) APPROVAL= AP YEAR= 1993 DISCONTINUED
NDA 064169 (pdf not found) INN (CEFAZOLIN SODIUM) CEFAZOLIN SODIUM (FRESENIUS KABI USA) APPROVAL= AP YEAR= 1998 DISCONTINUED
NDA 064170 (pdf not found) INN (CEFAZOLIN SODIUM) CEFAZOLIN SODIUM (FRESENIUS KABI USA) APPROVAL= AP YEAR= 1998 DISCONTINUED
NDA 050779 (label) INN (CEFAZOLIN SODIUM) CEFAZOLIN AND DEXTROSE (B BRAUN) APPROVAL= AP YEAR= 2000
NDA 065047 (pdf not found) INN (CEFAZOLIN SODIUM) CEFAZOLIN SODIUM (HIKMA FARMACEUTICA) APPROVAL= AP YEAR= 2001
NDA 065143 (pdf not found) INN (CEFAZOLIN SODIUM) CEFAZOLIN SODIUM (HIKMA FARMACEUTICA) APPROVAL= AP YEAR= 2004
NDA 065226 (pdf not found) INN (CEFAZOLIN SODIUM) CEFAZOLIN SODIUM (HOSPIRA INC) APPROVAL= AP YEAR= 2005 DISCONTINUED
NDA 065244 (pdf not found) INN (CEFAZOLIN SODIUM) CEFAZOLIN SODIUM (HOSPIRA INC) APPROVAL= AP YEAR= 2005 DISCONTINUED
NDA 065247 (label) INN (CEFAZOLIN SODIUM) CEFAZOLIN SODIUM (HOSPIRA INC) APPROVAL= AP YEAR= 2005 DISCONTINUED
NDA 065141 (label) INN (CEFAZOLIN SODIUM) CEFAZOLIN SODIUM (SAMSON MEDCL) APPROVAL= AP YEAR= 2006
NDA 065345 (pdf not found) INN (CEFAZOLIN SODIUM) CEFAZOLIN SODIUM (SANDOZ) APPROVAL= AP YEAR= 2007 DISCONTINUED
NDA 065395 (pdf not found) INN (CEFAZOLIN SODIUM) CEFAZOLIN SODIUM (AUROBINDO PHARMA) APPROVAL= AP YEAR= 2008 DISCONTINUED
NDA 065303 (pdf not found) INN (CEFAZOLIN SODIUM) CEFAZOLIN SODIUM (ACS DOBFAR) APPROVAL= AP YEAR= 2008
NDA 065306 (pdf not found) INN (CEFAZOLIN SODIUM) CEFAZOLIN SODIUM (ACS DOBFAR) APPROVAL= AP YEAR= 2008
NDA 065280 (pdf not found) INN (CEFAZOLIN SODIUM) CEFAZOLIN SODIUM (CEPHAZONE PHARMA) APPROVAL= AP YEAR= 2009 DISCONTINUED
NDA 065295 (pdf not found) INN (CEFAZOLIN SODIUM) CEFAZOLIN SODIUM (CEPHAZONE PHARMA) APPROVAL= AP YEAR= 2009 DISCONTINUED
NDA 065296 (pdf not found) INN (CEFAZOLIN SODIUM) CEFAZOLIN SODIUM (CEPHAZONE PHARMA) APPROVAL= AP YEAR= 2009 DISCONTINUED
NDA 203661 (pdf not found) INN (CEFAZOLIN SODIUM) CEFAZOLIN SODIUM (QILU ANTIBIOTICS) APPROVAL= AP YEAR= 2015
NDA 207131 (label) INN (CEFAZOLIN SODIUM) CEFAZOLIN IN DEXTROSE (BAXTER HLTHCARE CORP) APPROVAL= AP YEAR= 2015
NDA 201654 (pdf not found) INN (CEFAZOLIN SODIUM) CEFAZOLIN SODIUM (HOSPIRA) APPROVAL= AP YEAR= 2016 DISCONTINUED
NDA 209217 (pdf not found) INN (CEFAZOLIN SODIUM) CEFAZOLIN SODIUM (QILU ANTIBIOTICS) APPROVAL= AP YEAR= 2018
NDA 216109 (label) INN (CEFAZOLIN SODIUM) CEFAZOLIN SODIUM (HIKMA) APPROVAL= AP YEAR= 2022
NDA 211413 (label) INN (CEFAZOLIN SODIUM) CEFAZOLIN SODIUM (HQ SPCLT PHARMA) APPROVAL= AP YEAR= 2023